Association between extreme temperature exposure and COPD health outcomes in China: study protocol for a systematic review - Summary - MDSpire

Association between extreme temperature exposure and COPD health outcomes in China: study protocol for a systematic review

  • By

  • Jiaxin Xu

  • Peng Zhang

  • Yan Wang

  • Jianya Yang

  • Suyun Li

  • June 25, 2026

  • 0 min

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Objective:

To assess the relationship between extreme temperature exposures (heat and cold exposure) and COPD health outcomes in Chinese populations.

Approach:
  • Study Design: A systematic review and meta-analysis will be conducted, including observational studies that meet the inclusion criteria.
  • Data Sources: Literature search across multiple databases including PubMed, Web of Science, Embase, CNKI, WANGFANG Data, VIP, and Sinomed.
  • Quality Assessment: The Risk of Bias in Non-randomized Studies-of Environmental Exposure (ROBINS-E) assessment tool will be used to evaluate reporting, methodological, and evidence quality.
  • Analysis: Outcomes will be analyzed using narrative synthesis and R software.
Key Findings:
  • Extreme temperature events are increasing in frequency and intensity due to climate change.
  • COPD is a leading cause of death globally, with significant prevalence in China.
  • Existing evidence primarily from high-income countries indicates a relationship between extreme temperatures and COPD outcomes.
Interpretation:

The review aims to assess the relationship between extreme temperature exposures and COPD health outcomes in Chinese populations.

Limitations:
  • The review will only include observational studies, which may limit the strength of conclusions.
  • Potential publication bias may affect the results.
Conclusion:

This systematic review seeks to provide evidence on the impact of extreme temperature on COPD in China.

Sources:

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