To assess the relationship between extreme temperature exposures (heat and cold exposure) and COPD health outcomes in Chinese populations.
Approach:
Study Design: A systematic review and meta-analysis will be conducted, including observational studies that meet the inclusion criteria.
Data Sources: Literature search across multiple databases including PubMed, Web of Science, Embase, CNKI, WANGFANG Data, VIP, and Sinomed.
Quality Assessment: The Risk of Bias in Non-randomized Studies-of Environmental Exposure (ROBINS-E) assessment tool will be used to evaluate reporting, methodological, and evidence quality.
Analysis: Outcomes will be analyzed using narrative synthesis and R software.
Key Findings:
Extreme temperature events are increasing in frequency and intensity due to climate change.
COPD is a leading cause of death globally, with significant prevalence in China.
Existing evidence primarily from high-income countries indicates a relationship between extreme temperatures and COPD outcomes.
Interpretation:
The review aims to assess the relationship between extreme temperature exposures and COPD health outcomes in Chinese populations.
Limitations:
The review will only include observational studies, which may limit the strength of conclusions.
Potential publication bias may affect the results.
Conclusion:
This systematic review seeks to provide evidence on the impact of extreme temperature on COPD in China.