Assessment of Long-term Cardiovascular Health and Exercise Capacity in Athletes Post-COVID-19: Findings from the COSMO Study - Summary - MDSpire

Assessment of Long-term Cardiovascular Health and Exercise Capacity in Athletes Post-COVID-19: Findings from the COSMO Study

  • By

  • Jana Schellenberg

  • Lynn Matits

  • Johannes Kersten

  • Daniel A. Bizjak

  • Florian Horn

  • Johannes Hell

  • Sebastian Viktor Waldemar Schulz

  • Eric Schwarz

  • Johannes Kirsten

  • April 29, 2026

  • 0 min

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Objective:

To evaluate 12-month changes in cardiac structure, myocardial deformation, and cardiopulmonary performance specifically in athletes recovering from mild COVID-19.

Key Findings:
  • Cardiac structure and function remained stable over 12 months with no adverse remodeling, indicating a positive recovery trajectory.
  • A significant reduction in E/E′ medial was observed, while other diastolic indices showed no significant changes.
  • Cardiopulmonary performance was preserved with no significant changes in VO2peak or workload, reinforcing the stability of exercise capacity.
  • Baseline VO₂peak was the only independent predictor of follow-up VO₂peak, highlighting its importance in recovery.
Interpretation:

The study indicates that athletes recovering from mild COVID-19 do not exhibit long-term impairments in cardiac structure or exercise performance, supporting a safe return to sports for these individuals.

Limitations:
  • Small sample size may limit generalizability and statistical power.
  • Study focused only on athletes with mild COVID-19, excluding those with severe cases.
Conclusion:

Findings suggest stable cardiopulmonary outcomes at 12 months post-infection, reinforcing the safety of return to sport for asymptomatic athletes.

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