To evaluate whether the combination of passive leg raising (PLR) with skin blood flow (SBF) monitoring can predict microvascular fluid responsiveness specifically in septic patients requiring fluid expansion.
Key Findings:
ΔSBF-PLR was evaluated as a predictor of fluid responsiveness, defined as a > 15% increase in SBF after volume expansion, indicating its potential utility in clinical settings.
SBF monitoring showed significant associations with established clinical markers of tissue perfusion, suggesting its relevance in assessing patient status.
Interpretation:
The study suggests that combining PLR with SBF monitoring may enhance the assessment of fluid responsiveness in septic patients, potentially improving resuscitation strategies.
Limitations:
The study was conducted in a single center, which may limit generalizability to other settings and populations.
Non-standardized parameters for fluid infusion decisions could introduce variability, potentially affecting the reliability of the findings.
Conclusion:
Incorporating SBF monitoring with PLR may provide a more accurate assessment of microvascular fluid responsiveness in septic patients, aiding in personalized fluid therapy and improving clinical outcomes.
by Alexandra Morin, Tomas Urbina, Juliette Bernier, Lisa Raia, Vincent Bonny, Louai Missri, Jean-Luc Baudel, Pierre-Yves Boelle, Eric Maury, Jérémie Joffre, Hafid Ait-Oufella
