A dual-axis cisternal classification for congenital intracranial cystic lesions: implications for surgical strategy and long-term prognosis - Summary - MDSpire

A dual-axis cisternal classification for congenital intracranial cystic lesions: implications for surgical strategy and long-term prognosis

  • By

  • Maria Mihaela Pop

  • Dragos Bouros

  • Artsiom Klimko

  • Ioan Alexandru Florian

  • Cristian Ionel Abrudan

  • Ioan Stefan Florian

  • December 1, 2025

  • 0 min

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Objective:

To develop a dual-axis cisternal classification model for congenital intracranial cystic lesions, aiming to enhance surgical decision-making and predict clinical outcomes more effectively.

Key Findings:
  • Cisternal localization is independently associated with surgical complexity and extent of resection, influencing surgical strategies.
  • The dual-axis classification may provide better prognostic information compared to histological subtype alone.
  • A topography-informed risk stratification model was developed to enhance traditional histological classification.
Interpretation:

The dual-axis cisternal classification offers a valuable framework for surgical planning, potentially improving patient outcomes by providing a clearer understanding of lesion characteristics and their implications for treatment.

Limitations:
  • The study is limited to a single-center cohort, which may affect generalizability and introduce selection bias.
  • The reliance on MRI for classification may introduce variability in interpretation, affecting consistency.
Conclusion:

The dual-axis cisternal classification model enhances surgical decision-making for congenital intracranial cystic lesions and may improve long-term prognosis, suggesting avenues for future research.

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