Impact of scheduled cesarean sections on non-working days on maternal and neonatal outcomes: a retrospective cohort study based on propensity score matching - Summary - MDSpire
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Impact of scheduled cesarean sections on non-working days on maternal and neonatal outcomes: a retrospective cohort study based on propensity score matching
To investigate the impact of performing scheduled cesarean sections for term singleton pregnancies on working versus non-working days on maternal and neonatal outcomes.
Approach:
Study Design: This single-center retrospective cohort study included women with term singleton pregnancies who underwent scheduled cesarean sections at a hospital between January and December 2024, with surgeries scheduled between 08:00 and 18:00.
Participant Grouping: Participants were divided into working-day and non-working-day groups based on the date of surgery.
Propensity Score Matching: 1:1 nearest neighbor matching was used to balance confounding factors such as maternal age, gestational age, parity, prior cesarean deliveries, conception method, hypertensive disorders, gestational diabetes, and pre-pregnancy body mass index (BMI).
Outcome Comparison: Postoperative fever, neonatal transfer, surgical outcomes, and umbilical cord blood gas parameters were compared between groups.
Statistical Analysis: Multivariable linear regression analysis was performed to adjust for residual confounding.
Key Findings:
No significant differences in postoperative fever, neonatal transfer, surgical blood loss, postoperative hospital stay, antibiotic duration, or umbilical cord pH and lactate levels between groups (p > 0.05).
Surgery on non-working days was associated with a shorter operative duration (β = −3.82, 95% CI: −7.22 to −0.42, p = 0.029).
Interpretation:
In this study population, no statistically significant differences in short-term adverse maternal or neonatal outcomes were detected between scheduled cesarean sections performed on working and non-working days.
Limitations:
Single-center study may limit generalizability.
Sample size may not be sufficient to detect small differences.
Conclusion:
No statistically significant differences in outcomes were found between cesarean sections performed on working versus non-working days.
Federal prosecutors allege that a Florida physician and research staff fabricated clinical trial records that were submitted into database systems used to evaluate investigational drugs.