A randomized controlled trial of telemedicine and e-health interventions for the management of oral complications in oncology patients undergoing antineoplastic therapy - Summary - MDSpire

A randomized controlled trial of telemedicine and e-health interventions for the management of oral complications in oncology patients undergoing antineoplastic therapy

  • By

  • Pinelopi Petropoulou

  • Ioli Ioanna Artopoulou

  • Ioannis Kalemikerakis

  • Antonis Galanos

  • Ourania Govina

  • May 4, 2026

  • 0 min

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Objective:

To evaluate the effectiveness of a comprehensive dental intervention for the assessment and management of oral health in patients with solid tumors during cancer therapy using e-health applications, with a specific focus on comparing outcomes to standard oncology-based oral care.

Key Findings:
  • Telemedicine significantly improved oral-health outcomes and oral-care behaviors compared to controls, with p-values indicating statistical significance.
  • At mid-treatment and treatment completion, the intervention group showed lower rates of mucosal lesions, gingival bleeding, gingivitis, and dental caries.
  • Higher tooth-brushing frequency was observed in the intervention group.
Interpretation:

Telemedicine and e-health tools enable effective monitoring, early-stage detection, and oral self-care guidance, leading to improved oral health and well-being during and after cancer treatment, suggesting a need for broader implementation in oncology care.

Limitations:
  • The study was limited to a specific patient population (breast, lung, or colon cancer), which may not represent all cancer types.
  • Results may not be generalizable to all cancer types or treatment regimens, and potential biases or confounding factors were not fully addressed.
Conclusion:

Integration of structured teledentistry monitoring into oncology care was associated with improved oral health outcomes in patients undergoing antineoplastic therapy, compared to usual practice.

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