The Third Reader - Summary - MDSpire
Coming Soon: Introducing MDSpire News. Learn more
Conexiant’s news site is now MDSpire News. Learn more

The Third Reader

  • By

  • Kamran Mirza

  • September 8, 2026

  • 13 min

Share

Objective:

To explore the implications of patients accessing pathology reports directly and the challenges in understanding them.

Approach:
  • Study on Patient Understanding: A randomized study of 2,238 adults published in JAMA in early 2025 assessed comprehension of standard versus patient-centered pathology reports, finding significant differences in understanding.
  • Survey on Cancer Diagnosis Communication: A survey of 2,412 cancer patients conducted by Sheena Bhalla and colleagues at UT Southwestern in 2024 examined how patients learned about their diagnosis, revealing varied preferences for communication.
  • AI in Patient Communication: A prospective controlled trial published in Radiology in November 2025 evaluated the effectiveness of AI-generated simplified reports in improving patient comprehension, showing notable improvements.
Key Findings:
  • 39% of patients understood standard reports correctly, while 93% understood patient-centered versions (JAMA, 2025).
  • 7% of patients learned their diagnosis through an online portal, often alone and without immediate support (UT Southwestern, 2024).
  • AI can improve readability of medical reports but may still contain factual errors and omissions (Radiology, 2025).
Interpretation:

The shift in access to pathology reports has created a need for clearer communication tailored to patients, as traditional reports were not designed for patient understanding.

Limitations:
  • Patients often turn to AI tools for interpretation without clinician supervision, which can lead to misunderstandings.
  • AI-generated reports still require professional review to ensure accuracy and prevent misinformation.
Conclusion:

The evolving landscape of patient access to medical information necessitates new approaches to communication, balancing patient autonomy with the need for accurate understanding.

Sources:

Original Source(s)

Related Content