Screening strategies for the early detection of non-cardia gastric cancer in low- to moderate-prevalence regions: Asia-Pacific gastroesophageal cancer congress consensus 2026 - Summary - MDSpire
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Early Detection of Non-Cardia Gastric Cancer in Low- to Moderate-Prevalence Areas: 2026 Asia-Pacific Gastroesophageal Cancer Congress Consensus on Screening Strategies

  • By

  • Ayaka Takasu

  • Fumiaki Ishibashi

  • Rapat Pittayanon

  • Hon Chi Yip

  • James Weiquan Li

  • Munkhsaruul Bayaraa

  • Hyunsoo Chung

  • Do Hoon Kim

  • Kamin Harinwan

  • Quang Dinh Le

  • Adolfo Parra-Blanco

  • Paulo Kassab

  • Vincenzo Giorgio Mirante

  • José Murillo-Rodriguez

  • Regina Rie Imada

  • Renata Nobre Moura

  • Sabina Beg

  • Pedro Genaro Delgado-Guillena

  • Marta Rodriguez-Carrasco

  • Seung-Hun Chon

  • Chul S. Hyun

  • Grigorios Christodoulidis

  • Vo Duy Long

  • Zili Xiao

  • Sergey Kashin

  • Roman Kuvaev

  • Ian Yu-Hong Wong

  • Robert Bechara

  • Mitsuru Esaki

  • Waku Hatta

  • Motohiko Kato

  • Seiichiro Abe

  • Sho Suzuki

  • Kohei Takizawa

  • Joo Ha Hwang

  • Wai Keung Leung

  • Duc Trong Quach

  • Matsuda Satoru

  • Han-Kwang Yang

  • Takuji Gotoda

  • October 14, 2026

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Objective:

To develop standardized recommendations for non-cardia gastric cancer screening in regions with low to moderate gastric cancer prevalence.

Approach:
  • Scope: Regions were defined as having a combined-sex age-standardized gastric cancer incidence rate below 20 per 100,000 person-years, using GLOBOCAN 2022 estimates.
  • Evidence review: For 11 clinical questions, assigned authors searched English-language MEDLINE publications, summarized evidence, and assessed certainty using GRADE.
  • Consensus: Thirty-seven international experts participated in a modified two-round Delphi process. Consensus required at least 80% agreement.
Key Findings:
  • The consensus focused on early detection of non-cardia gastric cancer, excluding cardia and gastroesophageal junction cancers.
  • The report was developed to address uncertainty about screening strategies in low- to moderate-prevalence regions amid changing H. pylori prevalence and population risk.
Interpretation:

The article context describes the rationale and methods for an international consensus on screening strategies; it does not provide the final recommendations or their results.

Limitations:
  • The supplied context ends during the methods section and does not include the final consensus statements or voting results.
  • The literature review was limited to English-language publications indexed in MEDLINE.
Sources:

Original Source(s)

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