Six-session non-operative exercise program yields sustained benefits for up to 18 months in end-stage knee osteoarthritis: a retrospective cohort study - Summary - MDSpire

Six-session non-operative exercise program yields sustained benefits for up to 18 months in end-stage knee osteoarthritis: a retrospective cohort study

  • By

  • Wing Yip Lee

  • Linda Man Kuen Li

  • Naomi Cheuk Ying Chen

  • Chloe Sze Man Leung

  • Alan Yin Chung Tsui

  • Xueyou Zhang

  • Mingde Cao

  • Patrick Shu-Hang Yung

  • Michael Tim-Yun Ong

  • June 27, 2026

  • 0 min

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Objective:

To evaluate the long-term outcomes of a physiotherapist-led, supervised non-operative program (Structured Non-Operative Treatment Program, SNTP) in patients with end-stage knee osteoarthritis awaiting total knee replacement.

Approach:
  • Study Design: A retrospective cohort study involving 2243 end-stage knee OA patients in Hong Kong, assessing outcomes before, at the end of the intervention, and at one-year post-intervention.
  • Intervention: The SNTP included six supervised sessions over one year, focusing on aerobic training, resistance exercise, neuromuscular training, and health education.
Key Findings:
  • The SNTP led to significant improvements in functional outcomes and symptom relief in patients with end-stage knee OA.
  • Improvements were sustained for up to 18 months post-intervention.
Interpretation:

Limitations:
  • The study is retrospective and may be subject to selection bias.
  • Results may not be generalizable to all populations due to specific inclusion criteria.
Conclusion:

The SNTP demonstrates improvements in symptoms and function in patients with advanced knee osteoarthritis.

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