Images in Vascular Medicine: Multimodal imaging of adventitial cystic disease of the superficial femoral artery - Summary - MDSpire

Images in Vascular Medicine: Multimodal imaging of adventitial cystic disease of the superficial femoral artery

  • By

  • The Thoi Nguyen

  • Nga Thi Viet Nguyen

  • Minh Thai Nguyen

  • Quan Anh Nguyen

  • Hoa Thi Le

  • Linh Thi Dang

  • May 26, 2026

  • 0 min

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Objective:

To highlight the diagnostic value of multimodal imaging in identifying adventitial cystic disease (ACD) in a young patient presenting with exertional claudication.

Key Findings:
  • Duplex ultrasonography revealed significant stenosis of the distal left superficial femoral artery with a hypoechoic intramural lesion.
  • CTA showed segmental luminal narrowing and a hypodense lesion causing luminal compression.
  • MRI demonstrated characteristic features of ACD, including multiloculated cystic lesions and extrinsic compression of the arterial lumen.
  • Histopathology indicated a degenerative process with mucin-filled cysts and fibrous septa.
Interpretation:

Recognition of ACD's imaging features is crucial for differentiating it from atherosclerotic disease, especially in young patients without traditional cardiovascular risk factors.

Limitations:
  • The case study is based on a single patient, which may limit generalizability.
  • ACD is a rare condition, making it challenging to establish broader diagnostic criteria.
Conclusion:

This case highlights the importance of multimodal imaging in diagnosing ACD in young patients with exertional claudication.

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