C-reactive protein to albumin ratio as a predictor of early postoperative wound complications in patients undergoing posterior lumbar spine surgery - Summary - MDSpire

C-reactive protein to albumin ratio as a predictor of early postoperative wound complications in patients undergoing posterior lumbar spine surgery

  • By

  • Tao Niu

  • Haoran Zhang

  • Peng Xie

  • Shibin Shen

  • Haoran Huang

  • Zhenggang Zhou

  • Bin Wang

  • Jianlin Ma

  • May 28, 2026

  • 0 min

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Objective:

To evaluate the predictive value of preoperative C-reactive protein to albumin ratio (CAR) for postoperative wound complications in patients undergoing posterior lumbar spine surgery.

Key Findings:
  • Patients with wound complications had significantly higher BMI, aCCI scores, ASA scores, blood loss, operative duration, and drain retention time compared to controls.
  • The proportion of patients with a high preoperative CAR (≥0.9) was significantly greater in the case group (35.0%) than in the control group (25.0%).
  • CAR ≥0.9 was identified as an independent predictor of postoperative wound complications (fully adjusted OR: 1.753).
  • CAR remained a robust predictor in patients undergoing interbody fusion and multilevel surgery but not in those without interbody fusion.
Interpretation:

Preoperative CAR is a valuable and independent biomarker for predicting early postoperative wound complications after posterior lumbar spine surgery, particularly in complex procedures.

Limitations:
  • Single-center study may limit generalizability.
  • Retrospective design may introduce selection bias.
Conclusion:

Preoperative assessment of CAR may facilitate personalized risk stratification and clinical optimization to improve surgical outcomes.

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