C-reactive protein to albumin ratio as a predictor of early postoperative wound complications in patients undergoing posterior lumbar spine surgery - Summary - MDSpire
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C-reactive protein to albumin ratio as a predictor of early postoperative wound complications in patients undergoing posterior lumbar spine surgery
To evaluate the predictive value of preoperative C-reactive protein to albumin ratio (CAR) for postoperative wound complications in patients undergoing posterior lumbar spine surgery.
Key Findings:
Patients with wound complications had significantly higher BMI, aCCI scores, ASA scores, blood loss, operative duration, and drain retention time compared to controls.
The proportion of patients with a high preoperative CAR (≥0.9) was significantly greater in the case group (35.0%) than in the control group (25.0%).
CAR ≥0.9 was identified as an independent predictor of postoperative wound complications (fully adjusted OR: 1.753).
CAR remained a robust predictor in patients undergoing interbody fusion and multilevel surgery but not in those without interbody fusion.
Interpretation:
Preoperative CAR is a valuable and independent biomarker for predicting early postoperative wound complications after posterior lumbar spine surgery, particularly in complex procedures.
Limitations:
Single-center study may limit generalizability.
Retrospective design may introduce selection bias.
Conclusion:
Preoperative assessment of CAR may facilitate personalized risk stratification and clinical optimization to improve surgical outcomes.