FaReWell Depression – a randomized controlled trial of a physiotherapeutic program for the facial rehabilitation of wellbeing in depression - Summary - MDSpire

FaReWell Depression – a randomized controlled trial of a physiotherapeutic program for the facial rehabilitation of wellbeing in depression

  • By

  • M. Axel Wollmer

  • Hannah Lemke

  • Patricia Waldvogel

  • Insa Neumann

  • Kayleigh Keller

  • Veronika Nölle

  • Nathalie Dittmer

  • Maksim Lucic

  • Barbara Walss

  • Tillmann H.C. Krüger

  • Josef Hättenschwiler

  • May 25, 2026

  • 0 min

Share

Objective:

To evaluate the therapeutic potential of the FaReWell Depression program, which aims to improve symptoms of depression through facial rehabilitation targeting emotional expression.

Key Findings:
  • Significant reduction in depression severity in the intervention group compared to the control group, as measured by the Montgomery-Åsberg Depression Rating Scale (MADRS).
  • No significant differences in secondary outcome measures, including anhedonia and facial self-perception, indicating the need for further exploration of these aspects.
Interpretation:

The results suggest that a self-applied facial physiotherapeutic intervention may improve symptoms of depression, highlighting the necessity for further investigation into its efficacy and mechanisms.

Limitations:
  • Small sample size of 49 patients.
  • Short duration of the intervention (six weeks).
  • Secondary outcomes did not show significant group differences.
  • Lack of long-term follow-up to assess the sustainability of the intervention's effects.
Conclusion:

The FaReWell program shows promise as a novel treatment approach for depression, but further research is needed.

Original Source(s)

Related Content