To propose a personalized iodine delivery rate (IDR)-based contrast formula for coronary CT angiography (cCTA) and investigate the impact of injection rate on coronary enhancement, highlighting its significance over existing methods.
Key Findings:
Personalized IDR can optimize vessel enhancement while minimizing total iodine dose, potentially improving clinical outcomes.
Standardized injection rates of 3.5 mL/s and 5.0 mL/s were tested for their impact on coronary enhancement.
No extravasation events were recorded in both study groups, indicating safety.
Interpretation:
The study suggests that personalized IDR protocols can improve coronary artery visualization in cCTA, potentially leading to better patient outcomes, particularly in diverse patient populations.
Limitations:
The study was conducted at a single center, which may limit generalizability.
Exclusion of patients with renal dysfunction or known hypersensitivity may affect the applicability of findings, potentially skewing results.
Conclusion:
The proposed personalized IDR-based contrast formula could enhance coronary imaging quality while reducing iodine exposure, warranting further validation in larger cohorts.
