Ultrasound-guided preseptal hydrodissection with 5% dextrose in water for persistent botulinum toxin-associated ptosis: a technical protocol - Summary - MDSpire
Advertisement
Ultrasound-guided preseptal hydrodissection with 5% dextrose in water for persistent botulinum toxin-associated ptosis: a technical protocol
To present a systematic protocol for ultrasound-guided preseptal hydrodissection aimed at treating persistent blepharoptosis following botulinum toxin type A injections.
Key Findings:
Two patients with persistent BoNT-A ptosis, previously treated with conventional methods, showed progressive improvement post-procedure.
Marginal Reflex Distance 1 (MRD1) increased from 0 to 4 mm in one patient and normalized in the other.
Improvements were maintained at 3–6 months without additional treatment and no adverse events reported.
Interpretation:
The technique may serve as a minimally invasive adjunctive intervention for persistent BoNT-A-associated ptosis, though findings are preliminary and should be interpreted with caution.
Limitations:
Descriptive findings without controlled trials to establish efficacy and safety.
Small sample size with only two cases reported, limiting generalizability.
Conclusion:
The protocol standardizes a novel approach for managing persistent ptosis after BoNT-A treatment, warranting further investigation through prospective controlled trials to validate efficacy and safety.
