Case Report: Pulmonary brucellosis presenting as multiple cavitary lung lesions on imaging - Summary - MDSpire

Case Report: Pulmonary brucellosis presenting as multiple cavitary lung lesions on imaging

  • By

  • Tong Wang

  • Min Wang

  • Li Zhao

  • Guoke Tang

  • Lili Hou

  • May 7, 2026

  • 0 min

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Objective:

To present a case of bilateral cavitary lung lesions due to pulmonary brucellosis, emphasizing its rarity and the importance of accurate diagnosis and treatment in clinical practice.

Key Findings:
  • Pulmonary brucellosis can present with multiple cavitary lung lesions, which is rare and often misdiagnosed.
  • Metagenomic next-generation sequencing is effective for diagnosing brucellosis, providing a reliable alternative to traditional methods.
  • Prolonged combination antibiotic therapy can lead to significant clinical and radiological improvement, emphasizing the need for timely intervention.
Interpretation:

This case underscores the importance of considering pulmonary brucellosis in patients with cavitary lung lesions, particularly in those with potential zoonotic exposure, and highlights the need for awareness among healthcare providers.

Limitations:
  • The rarity of pulmonary brucellosis may limit generalizability to broader populations.
  • Diagnosis may be delayed due to non-specific symptoms and imaging findings, and previous antibiotic use may complicate diagnosis.
Conclusion:

Pulmonary brucellosis should be included in the differential diagnosis of cavitary lung lesions, and timely diagnosis and treatment can lead to favorable outcomes.

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