Erector spinae plane block for opioid sparing in children undergoing laparoscopic appendectomy: a randomized controlled trial - Summary - MDSpire

Erector spinae plane block for opioid sparing in children undergoing laparoscopic appendectomy: a randomized controlled trial

  • By

  • Ming-wen Yang

  • Yu-zhu Cai

  • Ling-li Zhang

  • Jun Wang

  • Ran Tang

  • Ying-ying Sun

  • May 1, 2026

  • 0 min

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Objective:

To evaluate the opioid-sparing effects, analgesic efficacy, and safety of erector spinae plane block (ESPB) in children undergoing laparoscopic appendectomy (LA) compared to standard multimodal analgesia.

Key Findings:
  • The ESPB group had significantly lower 24-hour hydromorphone consumption (32.8 ± 10.1 μg/kg vs. 72.9 ± 14.5 μg/kg; P < 0.001), a 55% reduction, with 75 participants analyzed.
Interpretation:

ESPB significantly reduces opioid consumption and postoperative pain in children undergoing LA, supporting its use in multimodal analgesia without increasing adverse events, which is crucial for improving postoperative care.

Limitations:
  • Single-center study may limit generalizability and diversity of the sample.
  • Follow-up duration was limited to 24 hours post-surgery.
Conclusion:

Bilateral ultrasound-guided ESPB at T8 is effective in reducing opioid use and managing postoperative pain in pediatric laparoscopic appendectomy.

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