To synthesize current evidence on AI applications for predicting adverse pregnancy outcomes and examine sources of algorithmic bias.
Approach:
Key Findings:
AI shows potential for improving early detection and management of adverse pregnancy outcomes, including preeclampsia, preterm birth, gestational diabetes, and fetal growth restriction, with predictive performance (AUROC values from 0.73 to 0.97).
Limited external validation across diverse populations and absence of prospective clinical impact trials constrain current evidence.
Interpretation:
AI applications in maternal healthcare must address algorithmic bias and ensure equitable implementation.
Limitations:
Heterogeneity in predictive performance across studies due to differences in datasets and model architectures.
Lack of rigorous multisite validation and cost-effectiveness analyses.
Evolving regulatory frameworks governing AI accountability.
Conclusion:
Achieving equitable implementation of AI in maternal health requires transparency, accountability, and health equity throughout the AI development and deployment lifecycle.