Objective:

To evaluate the influence of dominant intravertebral cement distribution on pain relief after unipedicular vertebroplasty specifically in patients with osteoporotic vertebral compression fractures.

Approach:

Key Findings:

• Mean VAS decreased from 7.63 to 3.31 (p < 0.001), with a mean change of 4.32, indicating significant pain relief.
• Pain relief varied significantly across zones, with Zone 4 showing the highest improvement.
• Dominant cement zone was a strong independent predictor of pain relief (p < 0.001).
• Complications occurred in 45.4% of cases, primarily cement leakage, without permanent neurological deficits.

Interpretation:

The dominant zone of cement distribution is a significant predictor of pain improvement post-vertebroplasty, suggesting its potential as a quality marker for the procedure, particularly in optimizing patient outcomes.

Limitations:

• Retrospective design may introduce bias, affecting the reliability of the findings.
• Single-center study limits generalizability of results to broader populations.
• Potential confounding factors not fully controlled may influence outcomes.

Conclusion:

Cement distribution within the vertebral body is crucial for pain relief following unipedicular vertebroplasty, highlighting the need for standardized procedural techniques to enhance patient outcomes.

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