To investigate short-term changes in hormonal, bone metabolic, and inflammatory markers after ultrasound-guided microwave ablation (MWA) in patients with hyperparathyroidism (HPT).
Approach:
Study Design: A prospective observational study involving 19 patients (14 with primary HPT, 5 with secondary HPT) who underwent MWA.
Measurements: Serum levels of intact parathyroid hormone (iPTH), calcium, phosphate, alkaline phosphatase (ALP), bone turnover markers, and inflammatory markers were measured at baseline, day 1, and month 1 post-ablation.
Key Findings:
iPTH and calcium decreased by day 1 (P < 0.001); iPTH remained reduced at month 1 (P < 0.001).
Calcium slightly increased by month 1 (P = 0.046).
Phosphate showed a borderline upward trend (P = 0.050).
