Longitudinal trajectories of urinary albumin-to-creatinine ratio and risk of proteinuria among Chinese patients with type 2 diabetes: a single−center retrospective cohort study - Summary - MDSpire

Longitudinal trajectories of urinary albumin-to-creatinine ratio and risk of proteinuria among Chinese patients with type 2 diabetes: a single−center retrospective cohort study

  • By

  • Qian Chen

  • Tieqiao Wang

  • Xiaoqing Tian

  • Qiankai Jin

  • Li Li

  • Yushan Mao

  • Guoqing Huang

  • June 2, 2026

  • 0 min

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Objective:

To investigate the dynamic trajectories of urinary albumin-to-creatinine ratio (UACR) in Chinese patients with type 2 diabetes mellitus (T2DM) and its association with proteinuria risk.

Key Findings:
  • Increased proteinuria risk was observed in mid-range normal (HR = 48.40, 95% CI: 14.67-159.67) and rising with fluctuation groups (HR = 509.56, 95% CI: 157.01–1653.70) compared to the low-normal group.
Interpretation:

Limitations:
  • The study is limited to a single center, which may affect the generalizability of the findings.
  • The retrospective design may introduce biases related to data collection and patient selection.
Conclusion:

Original Source(s)

Longitudinal trajectories of urinary albumin-to-creatinine ratio and risk of proteinuria among Chinese patients with type 2 diabetes: a single−center retrospective cohort study

  • by Qian Chen, Tieqiao Wang, Xiaoqing Tian, Qiankai Jin, Li Li, Yushan Mao, Guoqing Huang

  • June 2, 2026

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