Thrombus straddling the patent foramen ovale: a case report - Summary - MDSpire

Thrombus straddling the patent foramen ovale: a case report

  • By

  • Qin Jiangyan

  • Dan Li

  • Shi Mengrong

  • Hu Zitao

  • July 7, 2026

  • 0 min

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Objective:

To report a rare case of transseptal thrombus straddling a patent foramen ovale (TSFO) and highlight its diagnostic and management implications.

Approach:
  • Case Presentation: An 81-year-old woman with a history of recurrent exertional dyspnea was diagnosed with TSFO after contrast-enhanced cardiac CT revealed a thrombus across the interatrial septum.
  • Management: Anticoagulation therapy was initiated after shared decision-making, with follow-ups at 1, 3, and 12 months confirming clinical recovery.
Key Findings:
  • Contrast-enhanced CT angiography effectively identified TSFO in the context of acute pulmonary embolism.
  • The thrombus was dynamic and transient, highlighting the need for timely imaging.
  • The patient showed significant improvement with anticoagulation therapy, with follow-ups indicating no thromboembolic symptoms.
Interpretation:

This case illustrates the need for awareness of TSFO as a potential manifestation of paradoxical embolism in patients with a patent foramen ovale.

Limitations:
  • TSFO is a rare condition, making it difficult to generalize findings to broader patient populations.
  • The case is based on a single patient, limiting the applicability of the findings.
Conclusion:

Early identification and management of TSFO can prevent systemic thromboembolic events.

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