To assess the dynamics of regional and total bone mineral density (BMD) in patients with obesity undergoing laparoscopic sleeve gastrectomy (LSG), focusing on gender differences in bone health evolution.
Key Findings:
BMD decreased at almost all analyzed sites at 6 months post-LSG and continued to decline at 12 months.
Total BMD at 12 months was 1.220 g/cm2 compared to 1.292 g/cm2 at baseline (p<0.001).
Men experienced a more significant decline in BMD compared to premenopausal women at all sites except the head.
BMD decline correlated positively with BMI decline at 12 months (r=0.134, p<0.05).
Interpretation:
The study indicates that LSG is associated with a significant decline in BMD, particularly in men, highlighting the need for ongoing monitoring of bone health in patients post-surgery.
Limitations:
Retrospective design may introduce selection bias.
Limited follow-up duration may not capture long-term BMD trends.
Missing follow-up data may affect the robustness of findings.
Conclusion:
LSG leads to a notable decrease in BMD during the first year, with observed gender differences, necessitating further research on long-term bone health and potential interventions post-surgery.
