Predictors of functional outcome at 3 months in ischemic stroke patients with discharge disability following endovascular therapy: a multi-center observational cohort study of 836 patients - Summary - MDSpire

Predictors of functional outcome at 3 months in ischemic stroke patients with discharge disability following endovascular therapy: a multi-center observational cohort study of 836 patients

  • By

  • Mohammad Mofatteh

  • Xiao Xiao

  • Yimin Chen

  • Junyi Hu

  • Mingzhu Feng

  • Jicai Ma

  • Lue Chen

  • Sijie Zhou

  • Xiuling Zhang

  • Zunbao Xu

  • Jiale Wu

  • Yongting Zhou

  • Yuzheng Lai

  • Wenhong Peng

  • January 6, 2026

  • 0 min

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Objective:

To identify key baseline, clinical, and procedural predictors associated with achieving functional independence (mRS 0-2) by 3 months in patients discharged with functional dependence after EVT for acute ischemic stroke.

Key Findings:
  • Younger age and lower baseline stroke severity (NIHSS) are associated with better functional outcomes.
  • Successful reperfusion (mTICI 2b-3) correlates with improved recovery.
  • Social support and rehabilitation access are significant predictors of post-discharge recovery.
Interpretation:

Understanding predictors of recovery post-discharge is crucial for optimizing rehabilitation strategies and improving long-term outcomes for stroke survivors, enabling tailored interventions.

Limitations:
  • The study is retrospective and may be subject to selection bias.
  • Data was collected from a single country, which may limit generalizability.
  • Potential confounding variables may not have been controlled for in the study.
Conclusion:

Identifying predictors of functional recovery in stroke patients with discharge disability can enhance personalized management and resource allocation in rehabilitation.

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