Assessing peri-operative antibiotic administration practices amongst urologic surgeons performing holmium laser enucleation of the prostate worldwide - Summary - MDSpire

Assessing peri-operative antibiotic administration practices amongst urologic surgeons performing holmium laser enucleation of the prostate worldwide

  • By

  • Seyed Mohammad Mohaghegh Poor

  • Hafsa Asif

  • Darion Denis-Diaz

  • Eric Riedinger

  • Tasha Posid

  • Maxwell Newton

  • Michael Sourial

  • Mark Assmus

  • Amy Krambeck

  • Bodo Knudsen

  • Matthew Lee

  • March 13, 2025

  • 0 min

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Objective:

To assess surgeons’ preferences regarding the type and duration of peri-operative antibiotic practices around HoLEP and identify specific factors influencing these practices, such as practice setting and patient characteristics.

Key Findings:
  • 95.7% of urologists would prescribe a single-dose prophylactic antibiotic for patients without catheterization (p < 0.0001).
  • 48.6% of urologists would provide additional prophylaxis for catheterized/intermittently self-catheterizing patients (p < 0.0001).
  • Private practice surgeons prescribed more post-operative antibiotics compared to academic or hospital-employed surgeons (75.0% vs. 64.6% vs. 11.0%, p = 0.015).
  • Surgeons with more experience tended to prescribe shorter durations of antibiotic treatment (p < 0.05).
Interpretation:

There is variability in antibiotic prophylaxis practices among urologists performing HoLEP, influenced by practice setting and patient catheterization status.

Limitations:
  • Low response rate (5.3%) may limit the generalizability of findings, as it may not accurately represent the broader urologic community's practices.
  • Survey responses may not reflect actual clinical practices due to potential biases in self-reporting.
Conclusion:

Standardized guidelines for antibiotic prophylaxis in HoLEP are needed to minimize post-operative infections and improve patient outcomes, especially given the current variability in practices.

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