To conduct a bibliometric analysis of research trends in the relationship between subchondral bone and stem cells, highlighting its significance in advancing understanding in this emerging field.
Key Findings:
1,267 publications were included in the analysis, indicating a growing interest in this area.
Zhang Wei from China was the most prolific author with 15 publications, reflecting China's leading role in this research.
The Chinese Academy of Sciences had the highest number of publications (52) and centrality (0.19), underscoring its influence.
The most highly cited author was ZHEN GH, and AM J Sport Med was the most cited journal with a centrality of 0.31, indicating key sources of impactful research.
The most frequent keyword was 'mesenchymal stem cells', while 'cartilage' had the highest keyword centrality (0.27), suggesting focal areas of research.
Emerging research fronts included topics like monosodium iodoacetate, chitosan, and tissue engineering, indicating future directions.
Interpretation:
Research on the subchondral bone-stem cell relationship is gaining traction, with consistent themes around cartilage and bone repair, cell therapy, and tissue engineering, which are crucial for developing effective treatments.
Limitations:
The analysis is limited to English-language publications, which may exclude significant research published in other languages.
The search was restricted to specific databases, potentially missing relevant studies that could provide a more comprehensive view.
Conclusion:
The study highlights the evolving focus on the subchondral bone-stem cell relationship, identifying key research hotspots and suggesting specific directions for future studies, such as exploring novel therapeutic approaches and technologies.
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