To evaluate longitudinal changes in right ventricular (RV) and biatrial function in breast cancer patients using cardiac magnetic resonance (CMR) feature tracking (FT), highlighting the clinical significance of these changes.
Key Findings:
Anthracycline treatment led to significant changes in RV and biatrial strain parameters.
Early detection of myocardial functional impairment was possible using CMR strain analysis.
Atrial strain changes preceded ventricular function alterations, indicating potential early indicators of CTRCD.
Interpretation:
The study highlights the utility of CMR strain analysis in detecting early myocardial dysfunction in breast cancer patients undergoing anthracycline therapy, emphasizing the need for regular cardiac monitoring.
Limitations:
The study was limited to a specific patient population and treatment regimen.
Long-term outcomes and the clinical significance of detected strain changes were not assessed.
Conclusion:
CMR strain analysis is a valuable tool for early detection of myocardial impairment in breast cancer patients treated with anthracyclines, warranting further research to establish routine monitoring protocols.
