Objective:

To determine if lesion conspicuity on contrast-enhanced mammography (CEM) is independently associated with the likelihood of malignancy.

Approach:

Key Findings:

• The study included 476 CEM examinations with 563 enhancing lesions.
• Lesion conspicuity was graded as low, moderate, or high based on enhancement relative to background parenchymal enhancement.
• Positive predictive values (PPV) for malignancy were calculated for each level of conspicuity, with specific PPV percentages provided.

Interpretation:

The study aims to clarify the relationship between lesion conspicuity on CEM and the likelihood of malignancy.

Limitations:

• Retrospective design may introduce bias, potentially affecting the reliability of findings.
• Single-center study limits generalizability to broader populations.
• Potential for discrepancies in radiologist interpretations may impact the consistency of results.

Conclusion:

The findings contribute to understanding the role of lesion visibility in assessing breast cancer risk using CEM, suggesting that higher conspicuity may correlate with increased malignancy risk.

Sources:

• American College of Radiology BI-RADS Supplement for CEM
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