Gender differences in symptoms suggestive of diabetic gastroparesis in the West Bank: clinical insights from a cross-sectional study - Summary - MDSpire

Gender differences in symptoms suggestive of diabetic gastroparesis in the West Bank: clinical insights from a cross-sectional study

  • By

  • Diya Asad

  • Qusai Zreqat

  • Shahd T. Idais

  • Marah Hunjul

  • Bara'ah Huseein

  • Alaa Ayyad

  • Hamzeh M. I. Abugharbieh

  • Haroun Neiroukh

  • Areen Zuhour

  • Salsabeel M. Abukhalaf

  • Nour Al-Atrash

  • Roa Alzughayyar

  • Hussein Hallak

  • June 10, 2026

  • 0 min

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Objective:

To provide large-scale, region-specific data on gender differences in the prevalence and severity of diabetic gastroparesis (DGP) symptoms, highlighting the importance of understanding these differences for better management strategies among patients with type 2 diabetes mellitus (T2DM).

Key Findings:
  • Females had a higher prevalence of obesity and poorer glycemic control.
  • Female patients reported a significantly higher prevalence and severity of all gastroparesis symptoms compared to males, as confirmed by statistical analysis.
  • Logistic regression indicated that female gender is the only independent factor associated with severe DGP symptoms (OR: 2.38, p = 0.019).
Interpretation:

The study highlights that female gender is a significant factor in the prevalence and severity of DGP symptoms, suggesting implications for treatment, although the underlying mechanisms remain unclear.

Limitations:
  • The study is limited to a specific region (West Bank, Palestine) and may not be generalizable to other populations.
  • The reliance on symptom-based assessment tools like GCSI in resource-limited settings may affect diagnostic accuracy and introduce biases in self-reported data.
Conclusion:

Female gender is associated with a higher prevalence and severity of DGP symptoms, necessitating further research to understand the underlying mechanisms and inform gender-based management strategies.

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