Analysis of factors associated with cognitive impairment in elderly patients hospitalized with chronic heart failure - Summary - MDSpire

Analysis of factors associated with cognitive impairment in elderly patients hospitalized with chronic heart failure

  • By

  • Xiao-ying Jin

  • Han Li

  • Meng-dan Chu

  • Kai-xin Peng

  • Bo-wen Chang

  • Ke-han Hu

  • Zeng-feng Su

  • May 25, 2026

  • 0 min

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Objective:

To systematically investigate the prevalence of cognitive impairment (CI) and its associated factors among older inpatients with chronic heart failure (CHF).

Key Findings:
  • The prevalence of cognitive impairment among older CHF inpatients was 55.9%.
  • Independent risk factors for CI included age ≥ 80 years (OR = 6.122), sleep disturbance (OR = 2.870), diabetes (OR = 2.409), and elevated NT-proBNP (>1000 pg/mL).
  • Protective factors included education level of senior high school or above (OR = 0.186) and LVEF ≥ 50% (OR = 0.035).
  • LVEF was confirmed as the most influential variable affecting cognitive impairment.
Interpretation:

Cognitive impairment is prevalent in older CHF patients and is influenced by several clinical and demographic factors.

Limitations:
  • The study was conducted at a single center, which may limit generalizability.
  • Cross-sectional design restricts causal inferences.
Conclusion:

Cognitive impairment is highly prevalent among older inpatients with CHF, influenced by various risk and protective factors.

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