Roux-en-Y Gastric Bypass and Sleeve Gastrectomy Risk-Adjusted Safety Profiles after Previous Fundoplication: A 499-Patient MBSAQIP Analysis - Summary - MDSpire

Roux-en-Y Gastric Bypass and Sleeve Gastrectomy Risk-Adjusted Safety Profiles after Previous Fundoplication: A 499-Patient MBSAQIP Analysis

  • By

  • Pattharasai Kachornvitaya

  • Valentin Mocanu

  • Mélissa V. Wills

  • Juan S. Barajas-Gamboa

  • Salvador Navarrete

  • Ricard Corcelles

  • Andrew Strong

  • Suthep Udomsawaengsup

  • Matthew Kroh

  • Jerry Dang

  • November 22, 2025

  • 0 min

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Objective:

To evaluate the prevalence, perioperative safety, and predictors of serious complications, specifically anastomotic leaks, postoperative bleeding, and other events, in patients undergoing Sleeve Gastrectomy (SG) or Roux-en-Y Gastric Bypass (RYGB) after previous fundoplication.

Key Findings:
  • RYGB showed higher symptom resolution rates and lower recurrence of reflux compared to redo fundoplication, suggesting it may be a more effective option.
  • SG may exacerbate GERD but can be performed safely in selected patients post-fundoplication, highlighting the need for careful patient selection.
  • Limited comparative safety and outcomes data exist for SG and RYGB in revisional contexts, indicating a need for further research.
Interpretation:

RYGB is a favorable option for patients with obesity and GERD post-fundoplication, while SG may be considered in select cases despite potential GERD exacerbation; patient selection criteria should be clearly defined.

Limitations:
  • Lack of detailed information on specific types of fundoplication performed may affect the analysis.
  • Data restricted to a specific timeframe may limit generalizability, and potential biases inherent in retrospective analysis should be acknowledged.
Conclusion:

RYGB is recommended over SG for patients with obesity and GERD after failed fundoplication due to better safety profiles and outcomes; careful patient selection is crucial.

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