Case Report: A rare case of ocular giant cell arteritis with bilateral orbital inflammation and diagnostic challenges - Summary - MDSpire

Case Report: A rare case of ocular giant cell arteritis with bilateral orbital inflammation and diagnostic challenges

  • By

  • Alexandru N. Lerint

  • Oreoluwa E. Morakinyo

  • Jae Won Oh

  • Vijaya Lakshmi Valaparla

  • Xiangping Li

  • June 9, 2026

  • 0 min

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Objective:

To highlight the challenges in diagnosing and treating Giant Cell Arteritis (GCA) with atypical presentations, particularly bilateral orbital inflammation and other rare ocular symptoms.

Key Findings:
  • Bilateral orbital inflammation in GCA is rare and often underrecognized, with significant implications for diagnosis.
  • Neuroimaging provided critical diagnostic information despite normal inflammatory markers.
  • Temporal artery biopsy confirmed the diagnosis of GCA.
Interpretation:

The case illustrates the need for heightened awareness of atypical GCA presentations and the potential role of advanced imaging, such as MRI, in improving diagnostic accuracy and patient outcomes.

Limitations:
  • The study is based on a single case report, limiting generalizability.
  • Current diagnostic criteria may not adequately capture the full spectrum of GCA, necessitating further research.
Conclusion:

This case emphasizes the importance of considering GCA in patients with atypical ocular symptoms and the potential utility of MRI in diagnosis.

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