Neurological manifestations in people with HIV in HAART era: a cross-sectional multicenter study - Summary - MDSpire

Neurological manifestations in people with HIV in HAART era: a cross-sectional multicenter study

  • By

  • Lu Lu

  • Jian Hu

  • Peiyu Wang

  • Longting Du

  • Jing Xiao

  • Guoxiang Lu

  • Kui Zhou

  • Peng Chao

  • PoWuJu Wu

  • Zhiyong Zong

  • Liyu Chen

  • Lei Chen

  • Lin Chen

  • Dong Zhou

  • Weixi Xiong

  • May 1, 2026

  • 0 min

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Objective:

To define the range of neurological conditions in individuals living with HIV during the HAART era.

Key Findings:
  • 69% of participants were newly diagnosed with HIV.
  • Common neurological symptoms included headache (30%), dizziness (13%), and neurobehavioral symptoms (8%).
  • Intracranial infections (21%) were the most frequent discharge diagnoses, followed by cerebrovascular disorders (16%) and primary headaches (11%).
  • The three most frequently identified types of infections were viral (25%), tuberculosis (20%), and Treponema pallidum (10%).
  • Cognitive impairment was noted in 15% of participants, with 2% diagnosed with dementia.
Interpretation:

Neurological symptoms may serve as initial presentations of HIV in the HAART era, with intracranial infections being a significant concern.

Limitations:
  • Study conducted in a limited geographic area, which may affect generalizability.
  • Cross-sectional design limits causal inferences.
  • Potential biases in participant selection and reporting.
Conclusion:

The study underscores the importance of HIV screening in neurological contexts, highlighting the prevalence of neurological disorders in HIV patients.

Original Source(s)

Neurological manifestations in people with HIV in HAART era: a cross-sectional multicenter study

  • by Lu Lu, Jian Hu, Peiyu Wang, Longting Du, Jing Xiao, Guoxiang Lu, Kui Zhou, Peng Chao, PoWuJu Wu, Zhiyong Zong, Liyu Chen, Lei Chen, Lin Chen, Dong Zhou, Weixi Xiong

  • May 1, 2026

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