Granulomatous cutaneous T-cell lymphoma in a patient with atage IVB of mycosis fungoides: a case report and literature review - Summary - MDSpire
Coming Soon: Introducing MDSpire News. Learn more
Conexiant’s news site is now MDSpire News. Learn more

Granulomatous Mycosis Fungoides in a Stage IVB Patient: A Case Study and Review of Existing Literature

  • By

  • Zhu Lin

  • Jing Xue

  • Guozeng Ye

  • Shuang Li

  • Tingzhi Liu

  • Jiping Lang

  • Zhixin Zheng

  • Xiaoyan Li

  • Qinbo Wang

  • Junrong Chen

  • June 10, 2026

Share

Objective:

To explore the clinical and histological manifestations of granulomatous mycosis fungoides (GMF) and to emphasize the significance of distinguishing it from other granulomatous diseases and classic mycosis fungoides.

Key Findings:
  • The patient exhibited multiple erythematous lesions and palpable skin masses with ulceration.
  • Histological evaluation confirmed GMF, characterized by specific tumor cell markers including CD3+ positivity and CD7−, CD4−, and CD8− negativity.
  • The clinical presentation of GMF can mimic other inflammatory skin disorders, complicating diagnosis.
Interpretation:

The findings highlight the importance of accurate diagnosis and the need for awareness among physicians regarding GMF's distinct characteristics, particularly to avoid misdiagnosis.

Limitations:
  • The case study is limited to a single patient, which may not represent the broader population.
  • The clinical and histological features of GMF can overlap with other conditions, making diagnosis challenging.
  • Potential bias exists due to the focus on a single case.
Conclusion:

This report emphasizes the unique clinical and histological features of GMF and the necessity for careful differentiation from other conditions, underscoring the importance of awareness among healthcare providers.

Original Source(s)

Related Content