To analyze the short- and medium-term outcomes of Endoscopic Sleeve Gastroplasty (ESG) in older patients with obesity, highlighting the significance of this demographic.
Key Findings:
Eighteen patients aged 65 and older underwent ESG with no peri-procedural or post-procedural adverse events, indicating a favorable safety profile.
Median Excess Weight Loss (EWL%) at 6 and 24 months was 39% and 41%, respectively, demonstrating effective weight loss.
Median Total Body Weight Loss (TBWL%) at 6 and 24 months was 15.1% and 15.5%, respectively, which is clinically significant.
Statistically significant differences in EWL% and TBWL% were observed across follow-up visits, suggesting sustained weight loss.
Interpretation:
ESG appears to be a safe and effective weight loss intervention for older adults, with outcomes comparable to younger populations, potentially offering a viable alternative to traditional bariatric surgery.
Limitations:
Small sample size of only 18 patients, which may limit the generalizability of the findings.
Lack of long-term follow-up data for some patients, which could affect the assessment of sustained outcomes.
Conclusion:
ESG may serve as a viable option for older patients with obesity, particularly those who are not candidates for traditional bariatric surgery, emphasizing its role in managing obesity in this demographic.
by Maria V. Matteo, Vincenzo Bove, Valerio Pontecorvi, Martina De Siena, Gabriele Ciasca, Massimiliano Papi, Giulia Giannetti, Giorgio Carlino, Marco Raffaelli, Guido Costamagna, Ivo Boškoski