To evaluate the role of hiatal hernia (HH) in the development, progression, and treatment outcomes of Barrett’s oesophagus (BO), a condition that can lead to oesophageal adenocarcinoma.
Key Findings:
HH is strongly associated with BO development, especially in larger hernias (> 2–4 cm) and long-segment BO.
There is a potential trend towards dysplastic (abnormal cell growth) and malignant progression of BO in patients with HH.
HH may reduce the efficacy of radiofrequency ablation, necessitating more treatment sessions for larger hernias.
Surgical repair may benefit selected asymptomatic patients with hernias ≥ 4 cm and established BO.
Interpretation:
Current evidence supports HH as a significant risk factor for the onset of BO, with implications for its progression and management that require further investigation to inform clinical practice.
Limitations:
The review primarily included observational studies, which may limit the strength of the conclusions drawn.
Inconsistent data regarding the progression of BO in the context of HH may affect the reliability of the findings.
Conclusion:
Further research is needed to clarify the role of HH in BO management, particularly regarding surgical interventions, to enhance patient outcomes.