Objective:

To investigate the role of TWIST1 in cancer stem cell markers and epithelial-mesenchymal transition in esophageal squamous cell carcinoma.

Approach:

• Data Presentation: The article presented data through various figures, including images of GFP-YM-1 and GFP-KYSE-30 cells.

Key Findings:

• Concerns were raised about data integrity due to similarities identified in presented images, including overlapping images of different cell types.

Interpretation:

The Editors retracted the article due to a lack of confidence in the data and conclusions presented, following concerns about data integrity.

Limitations:

• Authors did not address the concerns raised regarding data integrity, and no response was received from the authors regarding the specific issues.

Conclusion:

The article was retracted due to issues with data presentation and integrity.

Sources:

• BMC Cancer