Association between treatment decisions and survival outcomes in lung cancer patients under a multidisciplinary team model: the impact of MDT-recommended treatment plans on treatment completion rates, survival time, and treatment conversion - Summary - MDSpire
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Association between treatment decisions and survival outcomes in lung cancer patients under a multidisciplinary team model: the impact of MDT-recommended treatment plans on treatment completion rates, survival time, and treatment conversion
To evaluate the impact of Multidisciplinary Team (MDT)-recommended treatment plans on treatment adherence and survival outcomes in lung cancer patients.
Key Findings:
MDT group had a higher treatment completion rate (86.09% vs. 68.57%, P = 0.002).
MDT group showed a lower treatment conversion rate (19.13% vs. 39.05%, P = 0.001).
MDT patients had longer median OS (45.21 vs. 28.64 months, P<0.001) and PFS (19.80 vs. 13.53 months, P<0.001).
MDT participation was an independent factor for improved OS (HR = 0.605, P = 0.009) and higher treatment completion likelihood (OR = 3.438, P = 0.002).
Interpretation:
The MDT model enhances treatment adherence and survival outcomes in lung cancer patients by facilitating more precise treatment selection.
Limitations:
Single-center study may limit generalizability.
Retrospective design may introduce selection bias.
Conclusion:
The MDT approach is associated with improved treatment adherence, delayed treatment conversion, and significantly better survival outcomes in lung cancer patients.
