To understand the impact of sodium fluoresceine on prognosis, postoperative outcomes (including neurological function and survival rates), and the effect on postoperative radiotherapy in patients undergoing surgical resection for brain metastases.
Key Findings:
Fluoresceine was used in 67% of cases, with surgeons reporting expected gross total resection (GTR) in 95% of cases, indicating a high confidence in the technique.
The median preoperative tumor volume was 11.7 cm3, suggesting a significant burden of disease.
Postoperative outcomes showed no increase in neurological damage with the use of fluoresceine, supporting its safety.
Interpretation:
The use of sodium fluoresceine may enhance the extent of resection of brain metastases without compromising neurological function, potentially leading to improved patient outcomes.
Limitations:
The study is retrospective and may be subject to selection bias, which could influence the generalizability of the findings.
Comparative data on the influence of fluoresceine on EOR discrepancies are limited, which may affect the interpretation of its effectiveness.
Conclusion:
Sodium fluoresceine appears to be a valuable adjunct in the surgical resection of brain metastases, facilitating greater resection rates while maintaining neurological integrity, potentially improving overall patient outcomes.
