Negative life events and depression: a moderated mediation model of mobile phone addiction and chronotype among medical undergraduate students in North China - Summary - MDSpire
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Impact of Adverse Life Experiences on Depression: Exploring the Role of Mobile Phone Dependency and Chronotype in Medical Students from Northern China

  • By

  • Yuxin Chen

  • Qiwei Wang

  • Yuhua Zhu

  • Siyu Li

  • Yueyang Hu

  • Zhengran Liu

  • September 7, 2026

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Objective:

To examine the associations between negative life events (NLEs) and depression in medical undergraduate students, assessing the indirect effect of mobile phone addiction and the moderating effect of chronotype.

Approach:
  • Study Design: Cross-sectional study with a stratified random sampling method involving 1,616 medical students in North China.
  • Data Collection: Participants completed four self-reported questionnaires: PHQ-9, MEQ-5, a self-designed measure of NLEs, and a self-designed measure of mobile phone addiction.
Key Findings:
  • Significant associations were found between depression and three dimensions of NLEs: study pressure, relationship setbacks, and employment pressure (P < 0.001).
  • NLEs had a significant indirect association with depression through mobile phone addiction.
  • Chronotype significantly moderated the indirect effect of mobile phone addiction on the relationship between NLEs and depression (P < 0.001).
Limitations:
  • The study's cross-sectional design limits causal inferences.
  • Self-reported measures may introduce bias.

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