Passenger lymphocyte syndrome following organ and stem cell transplantation: current insights and clinical implications - Summary - MDSpire

Passenger lymphocyte syndrome following organ and stem cell transplantation: current insights and clinical implications

  • By

  • Zhong-yu Kang

  • Xue-ya Han

  • Chun Liu

  • Wei Liu

  • Dai-hong Li

  • June 11, 2026

  • 0 min

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Objective:

To summarize the available literature on passenger lymphocyte syndrome (PLS), focusing on its incidence, immunohematologic mechanisms, clinical features, and management.

Approach:
    Key Findings:
    • Clarify that incidence rates are approximate and based on the studies reviewed.
    Interpretation:

    Remove unsupported conclusions about the need for standardized criteria and management strategies.

    Limitations:
    • Ensure limitations are directly sourced from the study findings.
    Conclusion:

    Remove the conclusion as it includes recommendations not explicitly stated in the source material.

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