Objective:

To assess the awareness and acceptance of antenatal RSV vaccines among postpartum women in Al-Madinah, Saudi Arabia.

Approach:

• Study Design: A hospital-based, cross-sectional study was conducted at two hospitals in Al-Madinah, Saudi Arabia.
• Participants: 400 postpartum women were surveyed using a validated 13-item questionnaire.
• Data Analysis: Multivariate binary logistic regression analysis was used to assess associations between demographic data and awareness and acceptance of the antenatal RSV vaccine.

Key Findings:

• 51% of participants were aware of RSV infection.
• 72.5% provided correct answers regarding the mode of RSV transmission.
• 40% perceived the seriousness of RSV infection for infants as high.
• 58% acceptance rate for receiving the RSV vaccine.
• Higher educational attainment (university or higher) was associated with lower acceptance of the RSV vaccine (odds ratio, 0.72; 95% confidence interval, 0.56–0.93).

Interpretation:

Maternal acceptance of the antenatal RSV vaccine was lower among highly educated women compared to those with lower education levels.

Limitations:

• The study was conducted in a specific region, which may limit generalizability.
• The sample may not represent all postpartum women in Saudi Arabia.

Conclusion:

The low acceptance rate of the RSV vaccine among highly educated women indicates a need for further studies.