Feasibility and relevance of urine culture during stone fragmentation in patients undergoing percutaneous nephrolithotomy and retrograde intrarenal surgery: a prospective study - Summary - MDSpire
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Feasibility and relevance of urine culture during stone fragmentation in patients undergoing percutaneous nephrolithotomy and retrograde intrarenal surgery: a prospective study
To evaluate the clinical relevance of urine cultures during stone fragmentation and their correlation with specific postoperative infectious complications, such as SIRS and sepsis.
Key Findings:
Stone and pelvic urine cultures were more accurate predictors of postoperative infections than bladder cultures, suggesting a need for revised screening protocols.
Bacteria released during stone fragmentation were detected in the irrigation fluid, indicating potential pathways for infection.
There was a significant correlation between urine cultures during stone fragmentation and the risk of postoperative SIRS, highlighting the importance of intraoperative monitoring.
Interpretation:
The study suggests that urine cultures obtained during stone fragmentation provide valuable information regarding the risk of postoperative infections, potentially guiding antibiotic prophylaxis and influencing clinical practice.
Limitations:
Single-center study may limit generalizability; further multicenter studies are needed to validate findings.
Sample size may not be sufficient to draw definitive conclusions, indicating a need for larger studies.
Conclusion:
Urine cultures during stone fragmentation are feasible and relevant for predicting postoperative infections, underscoring the need for improved preoperative infection screening methods in line with current guidelines.
by E. De Lorenzis, L. Boeri, A. Gallioli, M. Fontana, S. P. Zanetti, F. Longo, R. Colombo, M. Arghittu, S. Piconi, G. Albo, A. Trinchieri, E. Montanari
