Top 10 evidence-based essentials in radiology - Summary - MDSpire
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Top 10 evidence-based essentials in radiology

  • By

  • MDSpire News Staff

  • September 29, 2026

  • 3 min

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Objective:

To provide a summary of essential evidence-based resources in radiology for imaging selection, safety, screening, diagnosis, treatment, and reporting.

Approach:
  • ACR Appropriateness Criteria: Provides evidence-based guidance for imaging or treatment selection in specific clinical situations.
  • ACR Manual on Contrast Media: Guides radiologists on managing risks associated with contrast media, including patient risk assessment and preparation for adverse events.
  • ACR Manual on MR Safety: Offers safety practices for clinical and research MR environments, with recommendations subject to updates.
  • ACR BI-RADS v2025: Supports breast imaging reporting and performance evaluation across various imaging modalities.
  • GÖTEBORG-2 Prostate Cancer Screening Trial: Evaluated prostate cancer screening methods, showing reduced diagnoses of clinically insignificant prostate cancer with negative MRI results.
  • SCEMAM Trial: Assessed the addition of contrast-enhanced mammography to digital breast tomosynthesis, identifying cancers but increasing false-positive rates.
  • Floretyrosine F 18 (Pixclara): FDA-approved for distinguishing recurrent glioma from treatment-related changes in PET imaging.
  • Lutetium Lu 177 Vipivotide Tetraxetan (Pluvicto): FDA-approved for use in combination with therapy for PSMA-positive metastatic prostate cancer.
Key Findings:
  • ACR Appropriateness Criteria aids in imaging selection.
  • Contrast media management is crucial for patient safety.
  • BI-RADS v2025 enhances breast imaging reporting.
  • GÖTEBORG-2 trial shows MRI can reduce unnecessary biopsies.
  • SCEMAM trial indicates increased false positives with added contrast-enhanced mammography.
  • FDA approvals for Pixclara and Pluvicto enhance diagnostic capabilities.
Sources:

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