Gastrointestinal Bleeding Risk Associated With Pulse Pressure in Patients With Atrial Fibrillation: Retrospective Cohort Study - Summary - MDSpire

Association Between Pulse Pressure and Gastrointestinal Bleeding Risk in Atrial Fibrillation Patients: A Retrospective Cohort Analysis

  • By

  • Michel Abou Khalil

  • Carlo El Khoury

  • Yishi Jia

  • Maximilian Moersdorf

  • Christian Massad

  • Alex El Darzi

  • Yara Menassa

  • Mohammad Montaser Atasi

  • Ghassan Bidaoui

  • Hadi Younes

  • Ala Assaf

  • Mario Mekhael

  • Eli Tsakiris

  • Chanho Lim

  • Charbel Noujaim

  • Abboud Hassan

  • Yingshuo Liu

  • Mary Margot M Maleckar

  • Rodolfo A Montiel Quintero

  • Omar Kreidieh

  • Amitabh C Pandey

  • Han Feng

  • Qussay Marashly

  • Nassir F Marrouche

  • July 20, 2026

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Objective:

To investigate the association between pulse pressure and the risk of gastrointestinal bleeding in patients with atrial fibrillation.

Approach:
  • Study Design: Retrospective cohort analysis of atrial fibrillation patients.
  • Population: Patients diagnosed with atrial fibrillation.
  • Outcome Measures: Incidence of gastrointestinal bleeding events.
Key Findings:
  • Elevated pulse pressure is associated with an increased risk of gastrointestinal bleeding in atrial fibrillation patients.
Interpretation:

The findings suggest that pulse pressure may serve as a useful marker for assessing bleeding risk in atrial fibrillation patients.

Limitations:
  • Retrospective design may introduce bias.
  • Potential confounding factors not fully controlled.
Conclusion:

Pulse pressure could be a valuable parameter in evaluating bleeding risk among atrial fibrillation patients.

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