Objective:

To investigate the relationship between annual institutional volume of Impella procedures and in-hospital mortality in patients with cardiogenic shock.

Approach:

Key Findings:

• Overall in-hospital mortality was 43.5%, with lower mortality observed at higher volume institutions.
• Patients at Q4 institutions had significantly lower in-hospital mortality (adjusted OR 0.67) and 30-day mortality (adjusted OR 0.69) compared to Q1 institutions.
• An inverse, nonlinear association between annual institutional volume and in-hospital mortality was found, with significant reductions at approximately 24 cases per year.

Interpretation:

Higher annual institutional volume of Impella procedures is associated with improved patient outcomes, suggesting that consolidating procedures at experienced centers may enhance care for cardiogenic shock patients.

Limitations:

• Observational design limits causal inference and may include unmeasured confounders.
• Potential underreporting of complications at lower-volume centers.
• Long-term outcomes were not assessed.
• Findings may not generalize to other healthcare systems or later periods.

Conclusion:

A higher annual institutional volume is linked to lower in-hospital mortality in cardiogenic shock patients, supporting the consolidation of Impella use at experienced centers.

Source

Based on findings from:

Procedural volume and outcomes of Impella support in cardiogenic shock

Yuji Nishimoto, Atsushi Kikuchi, Yukihito Sato, Tetsuya Watanabe, Takahisa Yamada, Takaharu Hayashi, Masahiro Kumada, Yohei Sotomi, Yasushi Sakata. Critical Care, 2026.

https://link.springer.com/article/10.1186/s13054-026-06009-6

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This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.