To provide an overview of the evolution of the CyberKnife system from its introduction in 1994 through 2026, summarize target-tracking strategies, assess accuracy in both static and moving targets, and highlight its clinical applications, including re-irradiation settings, dose prescriptions, and survival outcomes.
Approach:
Technical Evolution: Review the advancements and components of the CyberKnife system from 1987 to 2026.
Recent Advances: Present the most recent technological advancements in the CyberKnife system.
Key Findings:
The CyberKnife system utilizes a 6 MV X-band linear accelerator on a robotic arm for high-dose radiation delivery.
It allows for frameless, semi-automated treatment with real-time motion tracking.
The system has undergone six generations of advancements since its introduction, improving accuracy and treatment efficiency.
The CyberKnife system is approved to treat both intracranial and extracranial tumors.
Interpretation:
Limitations:
The review does not provide specific clinical outcomes or comparative effectiveness data.
Potential challenges in implementation and accessibility of the technology are not detailed.
Conclusion:
The CyberKnife system has evolved significantly over three decades, enhancing its role in modern radiotherapy.