To share preliminary experience in the synergic use of navigated Transcranial Magnetic Stimulation (nTMS), Cortico-Cortical Evoked Potentials (CCEPs), and Direct Cortical Stimulation (DCS) for language mapping during brain tumor surgery, highlighting the potential impact on surgical outcomes.
Key Findings:
Successful integration of nTMS, CCEPs, and DCS showed a matching correspondence in identifying language-related cortical areas, suggesting improved surgical precision.
Average distance among nTMS, DCS, and CCEPs spots was 5.10 mm with a standard deviation of 1.08 mm, indicating high spatial accuracy.
Postoperative outcomes were satisfactory with no complications, supporting the safety of the integrated approach.
Interpretation:
The integration of nTMS, CCEPs, and DCS provides a comprehensive approach for language mapping, enhancing surgical precision and patient safety, with potential implications for future surgical protocols.
Limitations:
Preliminary nature of the study with a single patient case, limiting broader applicability.
Lack of negative spot data limits comprehensive statistical analysis, which may affect the robustness of the findings.
Conclusion:
The synergistic use of nTMS, CCEPs, and DCS may optimize surgical outcomes in brain tumor resections involving language areas.
