Objective:

To investigate the impact of intravenous tranexamic acid (TXA) on postoperative hidden blood loss (HBL) and C-reactive protein (CRP) levels in patients with lumbar disc herniation treated via Delta-channel interlaminar endoscopic discectomy.

Approach:

• Method: label
• Method: text

Key Findings:

• HBL in the TXA group was significantly lower than in the control group (p < 0.05).
• No significant differences in operation time, IBL, CRP, RBC, HB, HCT, APTT, PT, TT, FIB, PLT, and D-dimer between the two groups (p > 0.05).
• Univariate analysis revealed that TXA, TT, RBC, HB, and HCT were influencing factors for HBL, with TXA, TT, and HCT identified as independent predictors.

Interpretation:

Preoperative intravenous administration of TXA effectively reduces HBL in patients undergoing Delta-channel interlaminar endoscopic discectomy without significantly affecting postoperative CRP levels.

Limitations:

• Retrospective design may introduce selection bias.
• Single-center study limits generalizability of findings.
• Small sample size may affect statistical power.

Conclusion:

Preoperative TXA administration is associated with reduced HBL during Delta-channel interlaminar endoscopic discectomy and does not significantly affect postoperative CRP levels.