The Effects of Gastroesophageal Reflux Disease in East Asia and China from 1990 to 2021: Findings from the 2021 Global Burden of Disease Study - Summary - MDSpire

The Effects of Gastroesophageal Reflux Disease in East Asia and China from 1990 to 2021: Findings from the 2021 Global Burden of Disease Study

  • By

  • Chengying Zhu

  • Zeming Le

  • Zhanjun Lu

  • Zihao Guo

  • Guo Yu

  • Zhiyuan Cheng

  • Changjie Zhao

  • Rong Wan

  • Weiliang Jiang

  • Wenqin Xiao

  • January 31, 2026

  • 0 min

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Objective:

To examine changes in GERD disease burden over time within China and East Asia, investigate variations between countries, and forecast future trends using GBD 2021 data, highlighting the importance of these trends for public health planning.

Key Findings:
  • East Asia recorded 396,791,145 new GERD cases in 2021, 12.24% of the global total, indicating a significant regional health challenge.
  • China accounted for 32,387,866 new cases, 626,248 DALYs, and 81,327,260 prevalent cases, underscoring the need for targeted interventions.
  • From 1990 to 2021, China experienced a 55.24% increase in new GERD cases, highlighting a concerning trend that necessitates immediate public health action.
Interpretation:

The increasing burden of GERD in East Asia, particularly in China, reflects changing demographics and lifestyle factors, necessitating targeted public health strategies to address this growing health issue.

Limitations:
  • Data may not fully capture regional variations within countries, potentially skewing the understanding of GERD's impact.
  • Potential underreporting of GERD cases in certain demographics, which could affect the accuracy of the findings.
Conclusion:

The study highlights the rising burden of GERD in East Asia, emphasizing the need for effective management and prevention strategies tailored to regional characteristics.

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