To report a case of cutaneous Rosai-Dorfman disease (CRDD), a rare condition, affecting the left ear and evaluate the effectiveness of systemic glucocorticoid therapy.
Key Findings:
The patient was diagnosed with CRDD through histopathological and immunohistochemical analysis.
Combination therapy with methotrexate was ineffective and led to adverse effects.
Prednisone monotherapy resulted in significant improvement in skin lesions and hearing recovery, indicating its potential as a treatment option.
Interpretation:
This case illustrates that systemic glucocorticoid therapy can be effective in treating CRDD involving the ear, leading to resolution of symptoms and recovery of hearing, suggesting a need for further research.
Limitations:
The study is based on a single case report, limiting generalizability.
Long-term outcomes beyond 7 months are not reported, raising concerns about the durability of treatment effects.
Conclusion:
Systemic glucocorticoids may be a viable treatment option for CRDD affecting the ear, with potential for symptom resolution and hearing recovery, but further studies are needed to validate these findings.
